If alcohol and various drugs with addictive properties want to invade your body, capture your spirit and make you his slave, what is the first thing this addictive substance does?

The first thing he does is attack the reward system in the brain, causing a massive release of dopamine, adrenaline, opioid peptides, and other neurotransmitters that instantly give you a sense of satisfaction, euphoria, and pleasure, and at that moment the balancing forces among your neurotransmitters kick in.

Endogenous cannabinoids sense this abnormal neuronal activity and begin to secrete large amounts in preparation for the restoration of the nervous system that has been disrupted by the addictive substance. Endogenous cannabinoids bypass the synapse of the neuron and bind to the CB1 receptor, which is further forward than the synapse of the neuron, thus effectively blocking neurotransmitters, such as dopamine, within the neuron from passing through to the receptor in the other neuron, thereby blocking the receptors in the brain. This blocks the feeling of pleasure and excitement in the brain.

Endogenous cannabinoids also synergise with the inhibitory neurotransmitter GaBa, which effectively reduces the activity of the dopamine pathway through the link between neurons, restoring calm to the entire neuronal system.

Alcohol and addictive substance drugs have this effect, and the body is exposed to it from the beginning to the detoxification that follows, and this has the balancing act that endogenous cannabinoids play behind it. It becomes one of our key defences in keeping addictive substances at bay.

Endogenous cannabinoids are not at all as famous as dopamine, the source of desire, serotonin, oxytocin, the source of intimacy, and endorphins, he has a more unfamiliar academic name, ethanolamine arachidonic acid, a neurotransmitter in a non-traditional sense that many scientists refer to as the source of happiness.

There are many systems in our body, including the blood system, the respiratory system, the skeletal system, the muscular system, the nervous system, and a sixth system that modern medicine believes is the endocannabinoid system. The endocannabinoid system has receptors throughout the body, and when combined with CB1 receptors, it also regulates the body's immune system, improves pain, eliminates inflammation, and balances the body's functions.

The endocannabinoid system has the ability to balance a variety of neurotransmitters, and after it binds to the CB1 receptor, it determines whether to promote or inhibit the release of neurotransmitters such as dopamine serotonin oxytocin endorphins, glutamate GaBA, and others, depending on the state of the person at the time.

If the CB1 receptor is a lock, then endocannabinoids is the key to unlock the lock, the lock is opened can be arbitrary to promote or inhibit the transmission of various neurotransmitters, open the CB1 receptor, who is disguised as control of this control system, so strongly addictive substances to do the first thing is to open the lock, cannabis in the thc and endocannabinoids are the same nature, so the substance can be through the external influx into our nervous system.

It's as if you've been pleasuring yourself in some way for a while, and in order to prevent you from getting too high and losing your motivation, endogenous cannabinoids begin to inhibit your dopamine secretion, allowing the euphoric neurotransmitters to return to calm, and if you're depressed for a period of time when you're all out of motivation, this is when the endogenous cannabinoid system begins to promote dopamine secretion as well, with the serotonin glutamate joining in the mix, allowing for the creation of motivation towards your goals and a relatively pleasurable Emotional State.

From the perspective of brain science, emotion is the product of neurotransmitters and neurons working together, who mastered the neurotransmitter delivery method to deliver content, and delivery of the weight, who can affect the mood, and even change the mood.

Dr Margaret from the University of Toronto carried out a series of experiments on the effects of endocannabinoids on mood, and eventually discovered that endocannabinoids can regulate our emotional responses to anxiety depression guilt by controlling CB1 receptors, for example if you are feeling an unusually anxious and fearful state at the time, the endocannabinoid system immediately regulates positive neurotransmitters such as serotonin, oxytocin, endorphins, etc., to handle your anxiety fear, and other emotional states to restore your overall state of calm.

Regarding how endocannabinoids help us to withdraw from addictive substances, the endocannabinoid system, as mentioned at the beginning, at normal levels, is effective in regulating neurotransmitter secretion, and a study by Professor Allan of Louisiana State University in the United States has found that endocannabinoids modulate neurotransmitters according to the state of pain when withdrawing from an addictive substance, reducing the withdrawal response.

For example, endocannabinoids can increase dopamine levels to make withdrawal less painful, and endocannabinoids can reduce anorexia and nausea during withdrawal so that people can still enjoy good food and good health during withdrawal.

In the future, by eliminating the risk of addiction and the side effects of cannabis addictive substances, without destroying the endogenous cannabinoids produced naturally in our bodies, it will be possible to benefit mankind in the future, similar to the way herbs are naturally attuned to the human body, these methods of combating various illnesses through the use of herbs in conjunction with the body's attunement are very common in the early days of human society, and many of these records have proved that they are effective. These natural methods do not create dependence on them, and since they are not addictive and do not have many side effects, they should be researched and developed in depth in the modern world.

But the reality is the opposite, under the joint monopoly of unscrupulous capitalists and pharmaceutical companies, our research on endocannabinoids has been delayed for more than 30 years, and only in the last few years has it gradually come to the forefront of people's minds, and if we had a better endocannabinoid system in our bodies, and understood how to support the improvement of his ways, it would be possible for us to ward off unhealthy addictions whenever and wherever we want to and wean ourselves off of them in the future.

Some food additives and stimulants can seriously reduce the activity of endogenous cannabinoids, block their nutrient supply, so that the balance of the system is in a low-nutritional low level of the state, so that the state of the person is prone to stimulating food addiction, which leads to excessive obesity or endocannabinoid system disorders.

Then there is the industrial medical system under the promotion of special drugs, the core of the special drugs is fast to meet the requirements of today's society's fast-paced treatment, but it is also very easy to lead to hormone level disorders, thus affecting the endogenous cannabinoid system is out of balance, is still in a no stability of the nerves, prone to depression and disease and other psychological state, only to take a variety of drugs to make their own peace of mind, until the last It is easy to produce dependence on certain drugs.

The last one is the social pressure, in the Italian National Institute of Health research in 2010 found that still under long-term stress, the body will secrete a large amount of cortisol, and cortisol will have serious damage to the endogenous cannabinoids, resulting in its inability to complete the synthesis or release.

Endocannabinoids may have more important effects on people than you or I can imagine, and are even considered by many scientists to exist on top of the brain, especially his ability to engage in memory, analgesia, anti-inflammatory, balancing moods, and withdrawal from addictions, which simply have irreplaceable effects.